Chamberlain, South Dakota, named for a Milwaukee Railroad official, Selah Chamberlain, was incorporated as a city in 1882. Chamberlain is located at the crossroads of Interstate 90 and the majestic Missouri River in south central South Dakota. Because of its location, it is often considered the Gateway to the Old West. Chamberlain hosts a vibrant business district, great opportunities for boating, hunting and fishing enthusiasts, an excellent educational system, a first-rate medical facility, recreational facilities for all ages and is surrounded by rich Native American Culture.

Population: 2,387  County: Brule
Visit the Sanford Chamberlain Medical Center by clicking this link.